We fish out of Foxhaven Marina on Catawba Island. Catawba is right next door to Port Clinton. One of our crew has an Erie boat and we keep our camper up there all year.
If you're fishin' for smallies you can't beat softcraws. Expensive, but they're like candy for your "sweety" on Valentine's Day. Drop shotting is also a good system on the big water. One of the big Pro tournies there last summer had every pro fishing drop shots. Tubes are another otption. If walleyes are what you'll try most of the baitshop up there have a message board that will give general locations of where they've been "catchen'm" and what rig is working best. If you're on a charter, no worries, the Captain will put you on whatever you're after.
Erie is notorious for being rough and unpredictable. Be safe out there and good luck.
I fish it a lot but mostly for walleye, just started doing smallmouth last year with some very limited success.